<?xml version="1.0" encoding="utf-8" standalone="yes"?><rss version="2.0" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Neural Signals Lab</title><link>https://neuralsignalslab.org/</link><description>Recent content on Neural Signals Lab</description><generator>Hugo</generator><language>en-us</language><copyright>John Issa</copyright><atom:link href="https://neuralsignalslab.org/index.xml" rel="self" type="application/rss+xml"/><item><title/><link>https://neuralsignalslab.org/contact/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://neuralsignalslab.org/contact/</guid><description>&lt;p&gt;Case Western Reserve University&lt;br&gt;&#10;Neurosciences | School of Medicine&lt;br&gt;&#10;Cleveland, Ohio&lt;/p&gt;&#10;&lt;p&gt;Primary contact: &lt;a href="mailto:john.issa@case.edu"&gt;John Issa, MD-PhD&lt;/a&gt;&lt;/p&gt;</description></item><item><title/><link>https://neuralsignalslab.org/people/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://neuralsignalslab.org/people/</guid><description>&lt;div class="flex-ns gap-2 mb4"&gt;&lt;div class="fl w-100 ph3"&gt;&#10; &lt;h3 id="pi-john-b-issa-md-phd"&gt;PI: John B. Issa, MD-PhD&lt;/h3&gt;&#10;&lt;p&gt;&lt;img src="https://neuralsignalslab.org/images/John.jpg" &#10;alt="Click for info" &#10;style="cursor: pointer; max-width:300px;" &#10;onclick="document.getElementById('dialog-b312af7e3ef5806998d7e1f956a7176d').showModal()"&gt;&lt;/p&gt;&#10;&lt;dialog id="dialog-b312af7e3ef5806998d7e1f956a7176d" &#10; style="padding: 30px 25px 25px 25px; border: 1px solid rgba(255, 255, 255, 0.5); border-radius: 12px; width: 80%; max-width: 600px; color: #111; box-shadow: 0 8px 32px 0 rgba(0, 0, 0, 0.5); position: relative; cursor: pointer; background: rgba(255, 255, 255, 0.6); -webkit-backdrop-filter: blur(10px); backdrop-filter: blur(10px);"&#10; onclick="this.close();"&gt;&#10;&lt;p&gt;&lt;button style="position: absolute; top: 10px; right: 20px; font-size: 32px; background: none; border: none; cursor: pointer; color: #444; line-height: 1;" &#10;onclick="this.closest('dialog').close()"&gt;×&lt;/button&gt;&lt;/p&gt;</description></item><item><title>Research</title><link>https://neuralsignalslab.org/research/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://neuralsignalslab.org/research/</guid><description>&lt;hr&gt;&#10;&lt;h2 id="how-do-we-remember-what-we-experience"&gt;How do we remember what we experience?&lt;/h2&gt;&#10;&lt;p&gt;Every waking moment, our brain is receiving an intractably large amount of information: what we see, what we hear, what we feel. Somehow it must make sense of all that information and form a representation that can be recalled at a later time that captures what we experienced in a way that is meaningful and useful. We want to understand how populations of neurons represent various aspects of an experience, such as where you were, who you were with, what you ate, and if you would want to go back.&lt;/p&gt;</description></item><item><title>Resources</title><link>https://neuralsignalslab.org/resources/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://neuralsignalslab.org/resources/</guid><description>&lt;hr&gt;&#10;&lt;h3 id="findbn-integrated-iterative-algorithm-to-decompose-a-fluorescence-signal"&gt;FINDBN: Integrated Iterative Algorithm to Decompose a Fluorescence Signal&lt;/h3&gt;&#10;&lt;p&gt;an integrated iterative algorithm for decomposition of a fluoresence signal into neuropil, baseline, and estimated (deconvolved) activity&lt;br&gt;&#10;GitHub: &lt;a href="https://github.com/DombeckLab/Issa2023"&gt;findbn&lt;/a&gt;&lt;br&gt;&#10;Publication: &lt;a href="https://neuralsignalslab.org/pdf/Issa%20et%20al%20-%20Nat%20Neuro%202024.pdf"&gt;Issa et al - Nat Neuro 2024&lt;/a&gt;&lt;/p&gt;&#10;&lt;hr&gt;&#10;&lt;h3 id="imrsiv-miniature-rodent-stereo-illumination-vr"&gt;iMRSIV: Miniature Rodent Stereo Illumination VR&lt;/h3&gt;&#10;&lt;p&gt;virtual reality goggles for mice&lt;br&gt;&#10;GitHub: &lt;a href="https://github.com/DombeckLab/IMRSIV"&gt;iMRSIV&lt;/a&gt;&lt;br&gt;&#10;Publication: &lt;a href="https://neuralsignalslab.org/pdf/Pinke%20et%20al%20-%20Neuron%202023.pdf"&gt;Pinke et al - Neuron 2023&lt;/a&gt;&lt;/p&gt;&#10;&lt;hr&gt;</description></item><item><title>Selected Publications</title><link>https://neuralsignalslab.org/publications/</link><pubDate>Mon, 01 Jan 0001 00:00:00 +0000</pubDate><guid>https://neuralsignalslab.org/publications/</guid><description>&lt;!-- featured_image = "/images/neuroncover.jpg"&#10;header_section_class = "tc-l pv7 ph3 ph4-ns"&#10;omit_header_text = "true"&#10;featured_image_class = "cover bg-center"&#10; --&gt;&#10;&lt;!-- &lt;img src="https://neuralsignalslab.org/images/multiscalecolorful.jpg" width="150" height="150" style="display: block; margin: 0 auto;"&gt; --&gt;&#10;&lt;!-- &lt;div class="flex-ns gap-2 mb4"&gt;&lt;div class="fl w-third w-third-l ph3"&gt;&#10; &lt;img src="https://neuralsignalslab.org/images/neuroncover.jpg" height="auto" width="200"&gt;&#10;&lt;/div&gt;&#10;&lt;div class="fl w-third w-third-l ph3"&gt;&#10; &lt;img src="https://neuralsignalslab.org/images/multiscalecolorful.jpg" height="auto" width="200"&gt;&#10;&lt;/div&gt;&#10;&lt;div class="fl w-third w-third-l ph3"&gt;&#10; &lt;img src="https://neuralsignalslab.org/images/neuroncover2.jpg" height="auto" width="200"&gt;&#10;&lt;/div&gt;&#10;&lt;/div&gt;&#10;&#10; --&gt;&#10;&lt;hr&gt;&#10;&lt;p&gt;Visit &lt;a href="https://scholar.google.com/citations?user=ppypReoAAAAJ"&gt;&lt;span style="color: rgb(66, 133, 244);"&gt;G&lt;/span&gt;&lt;span style="color: rgb(234, 67, 53);"&gt;o&lt;/span&gt;&lt;span style="color: rgb(251, 188, 4);"&gt;o&lt;/span&gt;&lt;span style="color: rgb(66, 133, 244);"&gt;g&lt;/span&gt;&lt;span style="color: rgb(52, 168, 83);"&gt;l&lt;/span&gt;&lt;span style="color: rgb(234, 67, 53);"&gt;e&lt;/span&gt; Scholar&lt;/a&gt; for a complete list.&lt;/p&gt;&#10;&lt;div class="references-block"&gt;&#10;&lt;!-- &lt;img src="https://neuralsignalslab.org/images/neuroncover2.jpg" style="float: right; margin-right: 10px;" width="10%" height="10%"&gt; --&gt;&#10;&lt;p&gt;Davoudi, H, Climer, JR, Issa, JB, Dombeck, DA (2026). &lt;a href="https://neuralsignalslab.org/pdf/Davoudi%20et%20al%20-%20Neuron%202026.pdf"&gt;Distinct brain regions map olfactory and visual spaces&lt;/a&gt;. &lt;em&gt;Neuron&lt;/em&gt;. 114(15):2868-2883.&lt;/p&gt;</description></item></channel></rss>